supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Amoxicillin
supplement:
Glutathione
Research Papers that Mention the Interaction
“Consequently, we show that several thiol-containing compounds, including dithiothreitol, N-acetyl-L-cysteine, and glutathione , perform a nucleophilic attack on the amoxicillin molecule that is followed by an internal rearrangement leading to amoxicillin diketopiperazine, a known amoxicillin metabolite with residual activity.”
Amoxicillin Inactivation by Thiol-Catalyzed Cyclization Reduces Protein Haptenation and Antibacterial Potency“On the other hand, amoxicillin inhibited the activities of superoxide dismutase (SOD), GSH contents and the algal cell size in the exposure period while malonaldehyde (MDA) contents increased significantly in two periods.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback