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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Amobarbital
supplement:
Ubiquinone
Research Papers that Mention the Interaction
“Furthermore, titrations with Amytal , an inhibitor of NADH: CoQ oxidoreductase, revealed mild mitochondrial dysfunction in skeletal muscle tissue, which was described in patients with MND in an earlier report.”
Mitochondrial tRNA(Cys) mutation A5823G in a patient with motor neuron disease and temporal lobe epilepsy.“The reduction of coenzyme Q by the pyridinoprotein substrates is inhibited by Amytal as well as by antimycin A. The latter compound also inhibits the reduction of coenzyme Q by succinate.”
Studies on the electron transport system. XVI. Enzymic oxidoreduction reactions of coenzyme Q.“The phosphate-induced reduction of coenzyme Q is inhibited by both Amytal and antimycin A. These studies indicate that coenzyme Q, like DPN, acts as an electron carrier during the process of oxidative phosphorylation.”
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