Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 5 days ago

Possible Interaction: Amobarbital and NADH

supplement:

NADH

Research Papers that Mention the Interaction

Furthermore, titrations with Amytal , an inhibitor of NADH :CoQ oxidoreductase, revealed mild mitochondrial dysfunction in skeletal muscle tissue, which was described in patients with MND in an earlier report.
Pathobiology : journal of immunopathology, molecular and cellular biology  •  1999  |  View Paper
Oxidation of NADH was prolonged upon treatment with amobarbital , whereas no change in NADH oxidation was observed with malonate and nicotinamide.
Journal of neuroscience research  •  2004  |  View Paper
Inhibition of hydrogen transfer between NADH and Co Q by rotenone or amytal in salivary gland cells of Drosophila hydei maintained in vitro, results in the activation of a particular group of four loci in the polytene chromosomes (puff formation).
Chromosoma  •  2004  |  View Paper
The NADH oxidation occurred in the respiratory chain and it was selectively blocked by Amytal.
The American journal of physiology  •  1975  |  View Paper
The addition of NADH to reaction mixtures containing a NADPH-generating system increased the maximum velocities of amobarbital , hexobarbital, and pentobarbital by 77, 249, and 47%, respectively.
Drug metabolism and disposition: the biological fate of chemicals  •  1973  |  View Paper
Amytal and rotenone specifically blocked NADH oxidation, and respiration was also inhibited by KCN, antimycin A and thenoyltrifluroacetone.
Comparative biochemistry and physiology. B, Comparative biochemistry  •  1972  |  View Paper
Amytal partially inhibited the reduction of added cytochrome c by NADH 2 and had no effect on the reduction by malate.
Comparative biochemistry and physiology  •  1968  |  View Paper
The formation of DPNH is inhibited by Amytal , but not by oligomycin.
The Journal of biological chemistry  •  1967  |  View Paper
The rate of DPNH oxidation by oxygen is slightly inhibited by the addition of amytal , antimycin, or cyanide and greatly increased by cytochrome c. In the presence of cytochrome c, DPNH oxidation is potently inhibited by cyanide.
Archives of biochemistry and biophysics  •  1962  |  View Paper
Amytal partially inhibits oxidation of NADH but not phosphorylation.
European journal of biochemistry  •  1983  |  View Paper
Show More