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Last Updated: 3 years ago

Possible Interaction: Amobarbital and Glucose

supplement:

Glucose

Research Papers that Mention the Interaction

Addition of 2 mM amytal markedly decreased the islet energy level and eliminated the secretory response to 16 mM glucose.
The Journal of biological chemistry  •  1990  |  View Paper
With the latter substrate, in the presence of Amytal , the rates of mitochondrial ATP production were higher than those with glucose as the substrate.
The American journal of physiology  •  1979  |  View Paper
Treatment with amobarbital (0.16 mmol/kg) decreased the incorporation of glucose into acetylcholine by 73 × 7%, and treatment with atropine increased it by 18 × 6%.
Journal of neurochemistry  •  1978  |  View Paper
In the presence of amobarbital (used to preserve the function of the alpha-GOP shuttle under conditions where oxidation of NADH by the respiratory chain was blocked), glucose increased insulin secretion, O2 consumption, and the cell [ATP]/[ADP] when compared with amobarbital alone.
The American journal of physiology  •  1989  |  View Paper
Rotenone, cyanide and amytal also produce a rapid efflux of glucose from the membrane vesicles.
Folia microbiologica  •  1975  |  View Paper
In primary cells increased inhibition of O 2 uptake by Amytal is obtained in the presence of glucose , despite the fact that addition of glucose to non-inhibited cells increase O 2 uptake, while addition of palmitate to Amytal-inhibited cells increases O 2 uptake.
Biochimica et biophysica acta  •  1964  |  View Paper