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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Ammonium Chloride
supplement:
Glutathione
Research Papers that Mention the Interaction
“Administration of ammonium chloride (ammonia) via a microdialysis probe to the rat prefrontal cortex rapidly increased GSH content in the microdialysates.”
Direct exposure to ammonia and hyperammonemia increase the extracellular accumulation and degradation of astroglia-derived glutathione in the rat prefrontal cortex.“In this study, we show that intracerebral administration of ammonium chloride ("ammonia", final concentration 5mM) via a microdialysis probe, increases by 80% the glutathione content in cerebral cortical microdialysates, and tends to increase its content in striatal microdialysates.”
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