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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Furthermore, VAL leads to a significant reduction of serum ammonia (NH4+) and brain NH4+ concentration.”
[Changes in and modulation of receptor activity in hepatic encephalopathy].“Ammonia and valine influence the activity of serotonin receptors in membranes of frontal cortex taken from brain removed at postmortem: Ammonia reduces maximal binding capacity of serotonin receptors, and this effect can be antagonized by valine.”
“A very significant reduction after treatment with L-valine could be observed in glutamine and ammonia concentration.”
“It is suggested that L-valine has some beneficial action on ammonia detoxification and has also a competing action on amino acid uptake mechanism (specially with the large neutral amino acids).”
“The enzyme synthesis is significantly induced by L-valine but severely repressed by ammonia.”
Purification and characterization of a novel valine dehydrogenase from Streptomyces aureofaciens.“The enzyme was the only active VDH in S. fradiae; its activity was significantly induced by L-valine , but was repressed by ammonia.”
“ Ammonia caused large stimulatory effects in incorporation of (14)C into glutamine (a factor of 21), aspartate, asparagine, valine , alanine, arginine, and histidine.”
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