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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Ammonia and Tryptophan

drug:

Ammonia

supplement:

Tryptophan

Research Papers that Mention the Interaction

Ammonia , in addition to exerting potential toxic effects on the pineal gland [12], results in an increased entry of tryptophan into the brain, with alterations of serotonin (precursor of melatonin) and associated neurotransmission [13].
Annals of Internal Medicine  •  1995  |  View Paper
Hypothalamic concentrations of tyrosine and tryptophan were increased by the ammonia infusion and reduced significantly in insulin-treated infused rats.
Nutrition and cancer  •  1994  |  View Paper
Although Tk-TrpE displayed 47.6% similarity with TrpE of Salmonella typhimurium, conserved amino acid residues proven to be essential for inhibition of …, Met293, and Cys465 in the enzyme from S. typhimurium were replaced by Arg28, Thr221, and Ala384 in Tk-TrpE. Nevertheless, significant inhibition by L-tryptophan … ammonia ….
Biochemical and biophysical research communications  •  2001  |  View Paper