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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Basal phosphorylation of serines 890, 896 and 897 was increased in neurons exposed to ammonia , while NMDA-induced phosphorylation of S896 and S897 was reduced.”
Chronic exposure to ammonia alters basal and NMDA-induced phosphorylation of NMDA receptor-subunit NR1“The results indicate that serine as well as threonine cause a significant increase (p less than 0.01) of plasma ammonia and urinary orotate.”
“Furthermore, certain amino acids such as serine and cysteine were found to generate pyruvic acid that can be converted into acrylic acid and generate acrylamide when reacted with ammonia.”
Mechanistic pathways of formation of acrylamide from different amino acids.“During PR fixation, addition of ammonia caused decreased pools and labeling of glutamate and serine and increased glycolate, glyoxylate, and glycine labeling.”
“The degree of inhibition in some cases was dependent on the substrate concentrations: the sensitivity towards glycine, alanine and serine decreased with a decreasing ammonia level, while the sensitivity towards ADP or AMP increased with a decreasing ATP concentration.”
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