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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Ammonia and Phenylalanine





Research Papers that Mention the Interaction

Results showed that for the luminal bacteria, all AA concentrations except phenylalanine in the ileum decreased during the 24-h in vitro incubation with a increase of ammonia concentration, while 4 AA (glutamate, glutamine, arginine and lysine) in the jejunum decreased, with the disappearance rate at 60–95 %.
Amino Acids  •  2014  |  View Paper
They reduced the ammonia and glutamine concentrations in the blood and brains of the experimental animals and caused a significant decrease in the concentration of the aromatic amino acids ( phenylalanine and tyrosine) in the animals' brains.
Folia medica  •  1994  |  View Paper
There was a strong positive correlation between low plasma branched-chain amino acids and other essential amino acids, and a negative correlation between ammonia and phenylalanine to tyrosine (Phe:Tyr) ratio in patients with OTC deficiency, and between glutamine and Phe:Tyr ratio in all patients, indicating protein deficiency.
JIMD reports  •  2013  |  View Paper
Furthermore, the transcript level of one candidate gene (ARO10) increased 30-fold when phenylalanine replaced ammonia as the sole nitrogen source.
Applied and Environmental Microbiology  •  2003  |  View Paper
Glucose repressed enzyme synthesis, whereas ammonia reduced phenylalanine uptake and pool size and so may repress enzyme synthesis through inducer exclusion.
Journal of bacteriology  •  1982  |  View Paper