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Last Updated: 3 years ago

Possible Interaction: Ammonia and Orotic Acid




Orotic Acid

Research Papers that Mention the Interaction

Administration of either ammonia or glycine to both rats and mice results in an increased synthesis in the liver and urinary excretion of orotic acid.
European journal of biochemistry  •  1998  |  View Paper
For example, increased administration of amino acids, ammonia , certain disturbances in urea cycle enzymes and/or metabolites, and certain types of liver dysfunction result in increased synthesis of orotic acid.
Toxicologic pathology  •  1987  |  View Paper
The blood ammonia level was reduced by 47% when orotic acid was used instead of acetic acid.
Annales de recherches veterinaires. Annals of veterinary research  •  1979  |  View Paper
Ammonia , the only nitrogen source utilized by CPSase-I, markedly stimulated the incorporation of NaH14CO3 into orotic acid in liver slices, and ornithine, which enhances the intramitochondrial consumption of carbamoylphosphate (CP) in citrulline synthesis, antagonized the stimulation by ammonia.
Archives of biochemistry and biophysics  •  1977  |  View Paper