Possible Interaction: Ammonia and Methionine

“These results suggest at least that methionine and ammonia act synergistically on inducing hepatic encephalopathy.”

“The plasma concentrations of valine, leucine, isoleucine, phenylalanine, tyrosine, and methionine decreased after the ammonia load , whereas no changes were found in the plasma concentrations of glucagon and insulin.”

“Buthionine sulfoximine and acivicin, but not methionine sulfoximine, blocked the ammonia induced increase in GSH levels.”

“Cysteic acid, homocysteine and methionine , but not taurine reduced ammonia toxicity.”

“It is proposed that taurine has a general anticonvulsant action and that cysteic acid, homocysteine and methionine may have a specific effect on the action of ammonia on the central nervous system.”

“Among the compounds tested, the oligomerization reaction rate was accelerated by the presence of water and by an increase in pH. Ammonia also increased the oligomerization rate but consumed methionine by side reactions and resulted in the rapid degradation of methionine and its peptides.”

“Using the appropriate isotropic hexaammine complex … chemical shift difference between the ammonia protons , δ(ax) - δ(eq), is … sensitive to the paramagnetic metal ( M ), the remote diamagnetic metal (Cr or Re) and also to the donor properties … well as the counter-ion) as a result of hydrogen bonding interactions.”

“ConclusionsThese findings indicate that SeMet and SeMet + Vit-E may play an important role in reducing the accumulation of ammonia and subsequently in increasing the rate of AR and the utilization of glucose in porcine spermatozoa.”

“In contrast, the accumulation of ammonia was reduced by SeMet and SeMet + Vit-E compared with the other treatments.”

“In experiment 2, treatment of the sperm with SeMet and SeMet + Vit-E in the presence of 300 μM ammonia also resulted in a significant increase (P < 0.05) in the rate of motility, viability, AR and incorporation of 14C(U)-glucose.”

“ Ammonia production by immobilized cells with L-methionine-D ,L-sulfoximine (MSX) is greater than that of freeliving cells.”

“The poor nitrogen balance and level of urea and ammonia output of rats were significantly reduced when the protein-free, low-fat, low-caloric diet was supplemented with methionine ( 4 mg.”