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Discover Supplement-Drug Interactions

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Last Updated: 5 years ago

Possible Interaction: Ammonia and Citrulline

drug:

Ammonia

supplement:

Citrulline

Research Papers that Mention the Interaction

“Adding arginine, citrulline , and ornithine to EAA for a further four days significantly lowered the mean serum ammonia level.”
Journal of the Formosan Medical Association = Taiwan yi zhi  •  1994  |  View Paper
“ Citrulline supplementation may facilitate the detoxification of ammonia via the urea cycle and inhibit additional glycolysis.”
Journal of nutritional science and vitaminology  •  2011  |  View Paper
“Concomitant cellular concentrations of N-acetylglutamate were also drastically modified by the addition of ammonia as was the accumulation of citrulline.”
Biochemical and biophysical research communications  •  1984  |  View Paper
“The ammonia upshift has a general effect in Synechocystis, increasing the levels of many amino acids, notably glutamine, aspartate, arginine, and two arginine biosynthesis intermediates, ornithine and citrulline (4).”
mBio  •  2021  |  View Paper