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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Ammonia
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“In cultured rat microglia, ammonia stimulated cell migration and induced oxidative stress and an up‐regulation of the microglial activation marker ionized calcium‐binding adaptor molecule‐1 (Iba‐1).”
Microglia activation in hepatic encephalopathy in rats and humans“The results showed that ammonia exposure increased the release of calcium (Ca)2+ and reactive oxygen species (ROS) from mitochondrion.”
“We demonstrated that ammonia stimulated the production of intracellular reactive oxygen species, decreased mitochondrial membrane potential, interrupted intracellular calcium ion (Ca2+) homeostasis and induced cell apoptosis.”
“ Ammonia prevented glutamate-induced increase of intracellular calcium , depolarization of the inner mitochondrial membrane, release of cytochrome c to the cytosol, activation of caspase 3 and fragmentation of DNA.”
Ammonia prevents glutamate-induced but not low K+-induced apoptosis in cerebellar neurons in culture“At 2 mM or lower [phosphate] in the medium, calcium inhibited glutamine utilization and the production of glutamate, aspartate, and ammonia from glutamine.”
“With in vitro acidosis there was no change in glutamine uptake in the presence or absence of calcium but with calcium, ammonia production fell.”
“The addition of Ca immediately after phosphate resulted in the greatest reduction of ammonia acetate-exchangeable Ca concentration, Olsen-P concentration, and carbonate phase Pb.”
Lead retention in a calcareous soil influenced by calcium and phosphate amendments.“The complex formation by ammonia and Ca , coupled with the increase in pH, favors binding of calcium over that of magnesium by the cells.”
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