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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Amlodipine and Epigallocatechin Gallate

Research Papers that Mention the Interaction

It can be speculated that the drug-drug interaction between EGCG and amlodipine might occur, which might have resulted from the metabolism inhibition of amlodipine by EGCG when they were co-administered.
EGCG, … amlodipine increased from 16.32 ± 2.57 to 21.44 ± 3.56 ng/mL (p < 0.05), the Tmax decreased from 5.98 ± 1.25 … μg h L−1 (p < 0.05), which suggested that the pharmacokinetic behavior of amlodipine was affected after oral co-administration of EGCG.
Xenobiotica; the fate of foreign compounds in biological systems  •  2019  |  View Paper