Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Amitriptyline and Valine



Research Papers that Mention the Interaction

Amitriptyline caused decreased concentrations in rat plasma of the amino acids tyrosine and tryptophan, which … precursors to monoaminergic neurotransmitters, and also of those other large neutral amino acids (LNAAs) ( valine , phenylalanine, leucine and isoleucine) with which tyrosine and tryptophan compete … the carrier‐mediated transport from plasma into the brain.
The Journal of pharmacy and pharmacology  •  1995  |  View Paper