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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Amitriptyline
supplement:
Valine
Research Papers that Mention the Interaction
“ Amitriptyline caused decreased concentrations in rat plasma of the amino acids tyrosine and tryptophan, which … precursors to monoaminergic neurotransmitters, and also of those other large neutral amino acids (LNAAs) ( valine , phenylalanine, leucine and isoleucine) with which tyrosine and tryptophan compete … the carrier‐mediated transport from plasma into the brain.”
Effects of Amitriptyline on Rat Plasma and Brain Content of Monoamine Precursors and Other Large Neutral Amino Acids
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