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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Amitriptyline
supplement:
Sodium Bicarbonate
Research Papers that Mention the Interaction
“Conclusion Empirical treatment with sodium bicarbonate or hypertonic saline can reduce the development of cardiotoxicity during amitriptyline intoxication.”
Can empirical hypertonic saline or sodium bicarbonate treatment prevent the development of cardiotoxicity during serious amitriptyline poisoning? Experimental research“Alkalinization with NaHCO3 can effectively reverse ventricular arrhythmias caused by amitriptyline intoxication, but the mechanism is unclear.”
“However, the magnitude of improvement of phase 0 characteristics was significantly greater after high NaHCO3 and resulted in significant improvement of conduction velocity in fibers depressed by amitriptyline.”
“Physostigmine, propranolol, sodium bicarbonate , and left stellate ganglionectomy reversed the effect of amitriptyline on RET.”
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