Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Amitriptyline and Quinidine



Research Papers that Mention the Interaction

Plasma concentrations of AMI were not influenced by novobiocin, probenecid and the lack of Abcb1, but were significantly increased by quinidine , resulting from the inhibition of hydroxylation mediated by CYP2D6.
International journal of pharmaceutics  •  2009  |  View Paper
Absolute oral bioavailability (F) of amitriptyline was significantly increased more than three-fold in presence of quinidine (F = 0.6+/-0.4% versus 1.9+/-1.1%).
International journal of pharmaceutics  •  2007  |  View Paper