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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Amitriptyline
supplement:
Epinephrine
Research Papers that Mention the Interaction
“I present this case study as another example of drugs with alpha adrenergic receptor blocking activity (thioridazine and amitriptyline ) obstructing the action of adrenaline in anaphylactic collapse.”
Alpha adrenergic blockers and adrenaline. A mysterious collapse.“Chlorpromazine, amitriptyline and idazoxin inhibited larval metamorphosis induced by 10−4 M epinephrine.”
Larval metamorphosis of the mussel Mytilus galloprovincialis Lamarck, 1819 in response to neurotransmitter blockers and tetraethylammonium“Combined injection of amitriptyline with epinephrine in the threshold doses (ineffective if used alone), 1/10 and 1/30 minimum effective doses, respectively, leads to the development of the maximum analgesic and antidepressant effect, but causes no sedative side effect.”
“Coinjection of amitriptyline and bupivacaine with epinephrine enhances the analgesic duration of both drugs.”
“The results revealed that chronic treatment with amitriptyline resulted in significantly increased rises in delta [Ca2+]i after stimulation with 20 microM of carbachol or adrenaline , and a significant increase in muscarinic acetylcholine receptor density.”
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