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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Amitriptyline
supplement:
Choline
Research Papers that Mention the Interaction
“Acute administration of amitriptyline or atropine (highly potent anticholinergics) increased the level of high affinity uptake of choline in the hippocampus and striatum.”
Effects of acute and chronic administration of antidepressant drugs on the central cholinergic nervous system Comparison with anticholinergic drugs“Whereas blockade of dopamine receptors is likely to induce the observed alterations in high affinity choline uptake after administration of haloperidol, an antimuscarinic action may be involved in compensatory high affinity choline uptake increases after treatment with amitriptyline.”
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