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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Amitriptyline
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“ Amitriptyline caused increases in the concentrations of proteins, glycoproteins, calcium and potassium.”
Acute effects of some different antidepressant drugs on saliva composition.“In permeabilized myocytes, AMT transiently increased free luminal Ca concentration ([ Ca ]) followed by marked depletion.”
“In studies with cardiac SR microsomes, AMT slowed the rate of ATP-dependent Ca uptake.”
Tricyclic antidepressant amitriptyline alters sarcoplasmic reticulum calcium handling in ventricular myocytes.“4 Protriptyline and amitriptyline dose‐dependently inhibited TPA (1 μm)‐induced contraction in calcium‐free solution ; xylamine (up to 30 μm) was without effect.”
“ Amitriptyline increased the Ca concentration of nerve-evoked submandibular saliva, but had no effect on the Ca concentration of similarly evoked parotid saliva.”
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