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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Amiodarone
supplement:
Procaine
Research Papers that Mention the Interaction
“Pharmacologic interaction between amiodarone and procaine apparently is at least partly responsible for the increased Ca2 + uptake and the stone-heart phenomenon during reperfusion.”
“The combination of amiodarone and procaine or any class I antiarrhythmic drugs should therefore be avoided in cardioplegic solutions.”
Dose‐Dependent Cardiotoxic Effect of Amiodarone in Cardioplegic Solutions Correlates with Loss of Dihydropyridine Binding Sites: In Vitro Evidence for a Potentially Lethal Interaction with Procaine
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