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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Amiodarone
supplement:
Methionine
Research Papers that Mention the Interaction
“ AM significantly decreased slope of phase 4 depolarization (10.4% at 10−6 M, p < 0.05; 14.5% at 10−5 M , p < 0.01; 24.0% at 5 × 10−5 M, p < 0.01).”
“At 5 × 10−5 M, AM significantly decreased APA, maximum diastolic potential and threshold potential with an insignificant effect on APD100.”
“In …, AM increased APD90 by 9.6% (p < 0.01) at …−6 M, 13.7% (p < 0.01) at 10−5 M , and 16.9% (p < 0.01) at 5 × 10−5 M. The corresponding values for DAM were 5.6% (NS), and 7.3% (p < 0.01), respectively.”
Effects of Amiodarone and its Metabolite, Desethylamiodarone, on the Electrophysiologic Properties of Isolated Cardiac Muscle
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