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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Amiodarone
supplement:
Iodine
Research Papers that Mention the Interaction
“BACKGROUND AND OBJECTIVE The use of amiodarone for the treatment of ventricular and supraventricular dysrhythmias brings in organism an increased amount of iodine , interfering with thyroid function.”
The Role of Radiopharmaceuticals in Amiodarone-Induced Thyroid Pathology.“One of the problematic aspects of using amiodarone is the presence of two iodine molecules.”
“Formulations of the drug also contain iodine; the iodine content is 75 mg in a 200‐mg tablet of amiodarone and 18.7 mg/ml in the intravenous solution.”
“ Iodine and iodine-containing drugs (e.g radiographic contrast media, iodinated glycerol and amiodarone ) can have profound and variable effects on thyroid function.”
“Treatment of patients with amiodarone generates an iodine excess, which contributes greatly to the significant incidence of altered thyroid status in this population.”
“Treatment with amiodarone leads to an accumulation in the liver of this iodinated compound and hence an increase in the CT density of the liver.”
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