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Last Updated: 2 years ago

Possible Interaction: Amiodarone and Epinephrine

supplement:

Epinephrine

Research Papers that Mention the Interaction

Epinephrine infusion, at both 25 and 50 ng/kg per min, completely reversed the effects of quinidine and partially reversed the effects of amiodarone on the effective refractory period.
Journal of the American College of Cardiology  •  1992  |  View Paper
The number of electric shocks required for terminating VF, time to ROSC and adrenaline dose were significantly higher with amiodarone compared to nifekalant (p < 0.001).ConclusionsNifekalant showed a more favorable hemodynamic profile and improved survival compared to amiodarone and saline in this swine model.
Cardiovascular Drugs and Therapy  •  2015  |  View Paper
Amiodarone administered alone produces significantly lower coronary perfusion pressure than when combined with adrenaline.
Amiodarone combined with adrenaline produced pressures during CPR similar to adrenaline alone.
Resuscitation  •  2003  |  View Paper
Flecainide, E-4031, and verapamil markedly reduced the duration of arrhythmias induced by epinephrine, 8 µg/kg intravenously (P < 0.01), whereas only amiodarone markedly reduced the duration of arrhythmias Induced by epinephrine , 16 µg/kg intravenously (P < 0.01).
Anesthesiology  •  1993  |  View Paper