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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Amiodarone and Digitalis

supplement:

Digitalis

Research Papers that Mention the Interaction

It was often recommended to use amiodarone together with digitalis preparation in order to obtain its antiarrhythmic activity.
Wiadomosci lekarskie  •  2001  |  View Paper
Mechanism of action of this synergia is discussed, and the association of digitalis and amiodarone is recommended to reduce digitalization time in patients with paroxysmal auricular tachycardia.
Medicina clinica  •  1980  |  View Paper
These remarks are provided in addition to classical limitations of the association of amiodarone because of pronounced interactions with other nonantiarrhythmic drugs such as warfarin or digitalis , which also should have dosage reduced to prevent side effects.
Clinical cardiology  •  1987  |  View Paper
Further studies are warranted to understand the mechanism of the interaction between amiodarone and digitalis.
We found a statistically significant correlation between digitalis and amiodarone plasma level in patients on long term treatment with both drugs.
Giornale italiano di cardiologia  •  1981  |  View Paper
In patients with AF and appropriately treated CHF, attempting to maintain sinus rhythm with amiodarone and ECDV offered no benefit over rate control using -blockers with digitalis.
Annals of Internal Medicine  •  2008  |  View Paper