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Last Updated: 3 years ago

Possible Interaction: Amiodarone and Choline

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drug:

Amiodarone

supplement:

Choline

Research Papers that Mention the Interaction

“ Amiodarone produced a marked and significant (p less than 0.05) dose dependent reduction in choline uptake.”

Effect of antiarrhythmic drugs on choline uptake in cardiac cells in culture.

Cardiovascular research • 1992 | View Paper

“ Amiodarone but not desethylamiodarone produced a small but significant (P less than 0.05) increase in the amount of label that accumulated in CDP choline.”

“These data demonstrate that amiodarone and desethylamiodarone decrease choline uptake into cardiac cells that may potentially be involved in either the mechanism of action or toxicity of amiodarone.”

Effect of amiodarone and desethylamiodarone on choline uptake and phosphatidylcholine biosynthesis in cultured chick cardiac myocytes.

Journal of molecular and cellular cardiology • 1990 | View Paper

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