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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Amiodarone
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“ Amiodarone decelerated the inactivation of calcium ion current and accelerated the inactivation of potassium slow current.”
[Influence of RGPU-207 compound and amiodarone on ion currents in shellfish neurons].“Short incubation of hepatocytes with amiodarone (50 microM), 4,4'-diethylaminoethoxyhexestrol (50 microM) or perhexiline maleate (25 microM) increased the pool of CK8 monomers and increased cell calcium to activate Ca(++)-dependent transglutaminases which cross-linked the CK8 monomers into CK8-containing oligomers.”
“The inhibitory effect of amiodarone on L-type Ca2+ current may represent an important facet of amiodarone's acute antiarrhythmic activity in the immature heart.”
“ Amiodarone caused both a tonic and a phasic fuse-dependent) reduction of the Ca current.”
“ Amiodarone , an anti-arrhythmic drug with broad range microbicidal effect, has been shown to trigger a calcium burst in the yeast Saccharomyces cerevisiae.”
A spoke in the wheel: Calcium spikes disrupt yeast cell cycle“In addition to its four antiarrhythmic properties, amio darone may have complex effects on intracellular Ca 2 + stores and myocyte contractility.”
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