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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Aminosalicylic Acid
supplement:
Folate
Research Papers that Mention the Interaction
“Products of PAS metabolism at this and subsequent steps in folate metabolism inhibited those enzymes, competing with their substrates.”
Para-Aminosalicylic Acid Acts as an Alternative Substrate of Folate Metabolism in Mycobacterium tuberculosis“Our findings reveal that a metabolite of PAS inhibits DHFR in the folate pathway.”
“The mode of action of PAS , however, remains controversial as to whether it inhibits mycobactin or folate biosynthesis.”
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