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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Aminopyrine and Vitamin C


Vitamin C

Research Papers that Mention the Interaction

The distinct inhibitory action of ascorbic acid was verified under simulated conditions of the human stomach in further 9 drugs undergoing nitrosation at different rates, which contain the active agents: aminophenazone , clomipramine, imipramine, desipramine, ampicilline, oxacilline, phenoxymethylpenicilline, ethambutole or piperazine.
Archiv fur Geschwulstforschung  •  1985  |  View Paper
Vitamin C synthesis in rat liver is enhanced by several xenobiotics, including aminopyrine and chloretone.
Journal of Biological Chemistry  •  2003  |  View Paper
Additional in vivo studies demonstrate that simultaneous oral administration of ascorbic acid prevents the mutagenicity that follows the intragastric nitrosation of aminopyrine by nitrite while dietary pre-treatment with ascorbic acid does not.
Carcinogenesis  •  1985  |  View Paper
The administration of xenobiotics, PCB, DDT, or aminopyrine to rats causes a marked increase in urinary excretion of ascorbic acid and in various tissue levels of ascorbic acid.
The Journal of nutrition  •  1982  |  View Paper
Other types of compounds, such as chloretone, aminopyrine , meprobamate and phenylbutazone, also increase the urinary excretion of ascorbic acid in rats2,3.
Nature  •  1965  |  View Paper