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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Aminopterin and Thiamine



Research Papers that Mention the Interaction

79:827, 1960) presented evidence that aminopterin enters the cells of Bacillus subtilis mainly … active transport by the thiamine permease, and that the addition of small amounts of thiamine or a similar pyrimidine affords a great deal of protection against the growth inhibition caused by aminopterin (Pine, J. Bacteriol.
Journal of bacteriology  •  1965  |  View Paper
2) In washed-cell suspensions thiamin interferes with the uptake of aminopterin , but not of folic acid.
Biochemical pharmacology  •  1961  |  View Paper