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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Aminopterin and Methionine



Research Papers that Mention the Interaction

The growth inhibition by aminopterin was overcome in a noncompetitive fashion by the stepwise addition of methionine , adenine, and histidine.
Archives of biochemistry and biophysics  •  1957  |  View Paper
Addition of pteroylglutamic acid (PGA), homocysteine, Mg++, DPN, and ATP enhances the incorporation of serine-3-C14 into methionine, while addition of aminopterin or omission of PGA from the reaction mixture significantly decreases the incorporation of serine-3-C14 or formaldehyde-C14 into methionine.
Archives of biochemistry and biophysics  •  1957  |  View Paper