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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Aminopterin
supplement:
Methionine
Research Papers that Mention the Interaction
“The growth inhibition by aminopterin was overcome in a noncompetitive fashion by the stepwise addition of methionine , adenine, and histidine.”
Evidence for the involvement of folic acid in histidine synthesis in microorganisms.“Addition of pteroylglutamic acid (PGA), homocysteine, Mg++, DPN, and ATP enhances the incorporation of serine-3-C14 into methionine, while addition of aminopterin or omission of PGA from the reaction mixture significantly decreases the incorporation of serine-3-C14 or formaldehyde-C14 into methionine.”
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