Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago

Possible Interaction: Aminopterin and Histidine

supplement:

Histidine

Research Papers that Mention the Interaction

It was concluded from the above experiments that aminopterin blocks the synthesis of histidine in these microorganisms, and implies that folic acid coenzyme is concerned in the biosynthesis of histidine.
The growth inhibition by aminopterin was overcome in a noncompetitive fashion by the stepwise addition of methionine, adenine, and histidine.
Archives of biochemistry and biophysics  •  1957  |  View Paper