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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Aminophylline and Cocaine



Research Papers that Mention the Interaction

Mice with a history of chronic (10 days), but not acute, treatment with a non-convulsant dose of cocaine showed increased sensitivity (P<0.001) to the toxic effects of aminophylline (seizures, lethality) relative to controls even days after the cessation of cocaine treatment.
European journal of pharmacology  •  2000  |  View Paper
The effect of higher concentrations of aminophylline was even reversed by cocaine , procaine and lidocaine.
Archives internationales de pharmacodynamie et de therapie  •  1981  |  View Paper