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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Aminophylline
supplement:
Cocaine
Research Papers that Mention the Interaction
“Mice with a history of chronic (10 days), but not acute, treatment with a non-convulsant dose of cocaine showed increased sensitivity (P<0.001) to the toxic effects of aminophylline (seizures, lethality) relative to controls even days after the cessation of cocaine treatment.”
Lethal seizures predicted after aminophylline therapy in cocaine abusers.“The effect of higher concentrations of aminophylline was even reversed by cocaine , procaine and lidocaine.”
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