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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Aminolevulinic Acid and Caffeine

Research Papers that Mention the Interaction

Caffeine inhibits ALA synthetase activity, protecting heme, the natural repressor of this enzyme, from being destructed by AIA, as it appears from cytochrome P 450 levels reported in AIA treated animals.
Caffeine injection to animals treated with AIA markedly lowers ALA synthetase activity and causes an increase of cytochrome P 450 amount.
Pharmacological research communications  •  1974  |  View Paper