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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Aminoglutethimide and Epinephrine

Research Papers that Mention the Interaction

AG is now considered to act as an inhibitor of the aromatization of mainly adrenal androgens to estrogens in peripheral tissues and/or breast cancer itself.
The Journal of Steroid Biochemistry and Molecular Biology  •  1990  |  View Paper
Aminoglutethimide is an inhibitor of adrenal steroid biosynthesis and blocks the conversion of cholesterol to pregnenolone, and therefore reduces levels of adrenal androgens , which are a source of estrogens in both premenopausal and postmenopausal women.
Praxis  •  1998  |  View Paper
Glucocorticoids, synthetic steroidal antiandrogens, aminoglutethimide , ketoconazole, and spironolactone also may be used to block adrenal androgens.
Oncology  •  1991  |  View Paper
Treatment of murine epidermal cell preparations with epinephrine (EPI) or norepinephrine inhibited Ag presentation in vitro.
The Journal of Immunology  •  2002  |  View Paper