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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Aminoglutethimide
supplement:
Arachidonic Acid
Research Papers that Mention the Interaction
“Stimulation of these cells with Ag , carbachol, Ca(2+)-ionophore, or thapsigargin resulted in the phosphorylation of Raf1, MEK1, p42mapk MAP kinase, and the recently cloned cytosolic phospholipase A2 (PLA2) and increased activities of both MAP kinase and PLA2, as well as release of arachidonic acid.”
Activation of the mitogen-activated protein kinase/cytosolic phospholipase A2 pathway in a rat mast cell line. Indications of different pathways for release of arachidonic acid and secretory granules.“In untreated animals the levels of IL‐1 and TNF remained elevated until … after about 12 h. These studies demonstrate that the raised levels of arachidonic acid metabolites after … or AG seems to inhibit the otherwise lethal elevation of IL‐… in body fluids which is seen in untreated animals.”
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