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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“The effect of competition between two amilorides on yohimbine dissociation also was explored.”
Characterization of the allosteric interactions between antagonists and amiloride analogues at the human alpha2A-adrenergic receptor.“Allosteric modulation of [3H] yohimbine binding by Na+, H+, and 5-amino-substituted analogs of amiloride also was demonstrated for the alpha 2-receptor expressed in COS-M6 cells.”
“ Amiloride inhibited [3H]yohimbine and [3H]prazosin binding to alpha 2- and alpha 1-adrenoreceptors, respectively, from various tissues in a concentration-dependent manner.”
“ Amiloride inhibited [3H]yohimbine binding noncompetitively and [3H]prazosin binding competitively.”
“ Amiloride was approximately 9-12 times more potent in inhibiting [3H]yohimbine binding to alpha 2-adrenoreceptors from rat tissues than from other mammalian tissues.”
“Further, in rat tissues, amiloride was approximately 10 times more potent in inhibiting [3H]yohimbine than [3H]prazosin binding.”
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