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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Amiloride and Potassium



Research Papers that Mention the Interaction

Replacing a potassium supplement with amiloride increased the antihypertensive effect.
European Journal of Clinical Pharmacology  •  2004  |  View Paper
In both of these disorders, despite the rise in plasma potassium levels, amiloride produced a counter-therapeutic rise in PA which could potentiate further potassium losses.
Clinical and experimental hypertension. Part A, Theory and practice  •  1983  |  View Paper
A comparison with the results of an earlier study, in which hydrochlorothiazide was given without amiloride, showed that the intracellular potassium depletion and the increase in intracellular sodium concentration, observed with the benzothiazide diuretic, could be fully prevented by simultaneous administration of amiloride.
Acta medica Scandinavica  •  1975  |  View Paper
At submaximal dosages, amiloride potentiated the natriuresis and reduced the potassium loss evoked by ethacrynic acid.
Clinical pharmacology and therapeutics  •  1969  |  View Paper
Amiloride can be considered in serious potassium loss.
Journal of pediatric hematology/oncology  •  2004  |  View Paper
In one prospective, controlled study of hypokalemia with AmB administration, patients receiving concomitant amiloride had significantly greater potassium concentrations (p < 0.01) and required significantly less potassium supplementation (p < 0.001).
The Annals of pharmacotherapy  •  2000  |  View Paper
Plasma potassium rose significantly on amiloride (3.64 +/- 0.24 vs 4.07 +/- 0.54 mmol/l, P < 0.05).
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association  •  1998  |  View Paper
The decrement in potassium loss during concomitant amiloride treatment cannot be explained.
Clinical pharmacology and therapeutics  •  1984  |  View Paper
Amiloride caused a significant rise in exchangeable potassium , exchangeable potassium/kg body weight, and plasma potassium, together with a significant fall in plasma total carbon dioxide, body weight, systolic and diastolic blood pressures.
Postgraduate medical journal  •  1978  |  View Paper
Patients who were given amiloride needed less potassium supplementation than those in the control group (P< o oo5) and yet maintained significantly higher plasma potassium levels (P< o os).
British heart journal  •  1974  |  View Paper
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