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Last Updated: 3 years ago

Possible Interaction: Amiloride and Oxytocin

supplement:

Oxytocin

Research Papers that Mention the Interaction

After the administration of oxytocin, amiloride increased urinary flow from 4.3 ± 0.6 μl/min to 48.8 ± 6.1 μl/min.
Amiloride administered during an oxytocin infusion increased sodium excretion from 0.1 ± 0.0 to 16.6 ± 2.1 μmol/min.
Amiloride administrated after reaching a near steady-state effect of oxytocin was found to give rise to an effect far greater than that after the administration of oxytocin or amiloride alone.
Clinical and experimental hypertension  •  2008  |  View Paper
They were completely prevented by Amiloride (5 · 10−5 M), increased by oxytocin (20 mU/ml) and markedly dependent upon the outer Na concentration.
Pflügers Archiv  •  2004  |  View Paper
The increase of contraction due to oxytocin in choline medium is inhibited by amiloride (50 microM and 1 mM) and when calcium is suppressed of the incubation medium.
General pharmacology  •  1991  |  View Paper