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Last Updated: 3 years ago

Possible Interaction: Amiloride and Glucose



Research Papers that Mention the Interaction

The channels are inhibited by amiloride (1 mM), which further blunts annexin binding following osmotic shock, oxidative stress and glucose depletion.
Cell Death and Differentiation  •  2003  |  View Paper
Amiloride (0.1 mM), an inhibitor of Na(+)‐H+ exchange, prevented the effect of glucose on the ouabain‐resistant Na+ efflux, increasing the rate of outward transport in the absence of the sugar.
The Journal of physiology  •  1991  |  View Paper
The specific and Na(+)-dependent 'overshoot' in D-glucose concentration, in vesicles prepared from HKD rats, became sensitive to amiloride action (10(-5) M).
Biochimica et biophysica acta  •  1991  |  View Paper
The stimulation of transport by fructose in 0.05 M KCl and by D-glucose in 0.05 M RbCl was also inhibited by amiloride , demonstrating that the saccharide-stimulated entry pathway was specific for neither hexose sugars nor for Na.
The American journal of physiology  •  1989  |  View Paper
The inhibition of net fluid reabsorption by perfusion with a modified KRB buffer containing amiloride or by addition of ouabain to the bath medium raised glucose production rates to levels equaling or exceeding those observed in unperfused tubules.
The American journal of physiology  •  1989  |  View Paper
Transepithelial current evoked by glucose , fructose, or sucrose in either 30 mM NaCl or in Krebs-Henseleit buffer (K-H) was partially blocked by amiloride.
The Journal of general physiology  •  1988  |  View Paper
Amiloride reproduced the effect of glucose to decrease 86Rb and 45Ca outflow.
In the presence of glucose (5.6 mM or more), amiloride (100 microM) acted synergistically with the sugar to reduce K+ outflow, and to stimulate 40Ca inflow and insulin release from perifused islets.
Biochimica et biophysica acta  •  1986  |  View Paper
Regulation of pHi appears to occur by Na:H and HCO3:… exchange in the plasma membrane, because inhibition by 0.1 mM amiloride and 0.5 mM 4,4'-diisothiocyano-2,2'-stilbene disulfonic acid (DIDS), respectively, induces constant spike activity in the presence of 11.1 mM glucose.
Federation proceedings  •  1984  |  View Paper
DIDS and amiloride increased glucose-induced EA, but markedly inhibited the secretory response to glucose.
The American journal of physiology  •  1983  |  View Paper
However, both amiloride and EIPA were found to inhibit the incorporation of radioactivity from labelled glucose in S. pombe, with IC50 values of 879 and 272 microM for amiloride and EIPA respectively.
Biochimica et biophysica acta  •  1993  |  View Paper