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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Amiloride and Gamma-Aminobutyric Acid

Research Papers that Mention the Interaction

Amiloride acted primarily as a competitive antagonist, reducing the sensitivity of the receptor to GABA without affecting the maximal current amplitude.
Molecular pharmacology  •  2002  |  View Paper
On the basis of these results we conclude that amiloride and verapamil inhibit high K+-induced release of [3H]GABA by antagonizing the entrance of Ca2+ (and possibly Na+ when external Ca2+ is absent) through a population of voltage sensitive presynaptic Ca2+ channels activated by depolarization.
Neurochemical Research  •  2004  |  View Paper
Drugs such as acetazolamide or amiloride can block GABA depolarization.
Anesthesiology  •  1999  |  View Paper