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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Amiloride and Digitalis



Research Papers that Mention the Interaction

In prior studies, we have shown that the antikaliuretic drugs, triamterene and amiloride , through a direct cardiac effect reduce the loss of cardiac potassium induced by the administration of digitalis.
These studies have demonstrated that through a cardiac effect, by reducing the digitalis-induced loss of cardiac potassium, the potassium-sparing drugs, triameterene and amiloride , extend the toxic dose of digitalis and thus permit txtension of its inotropic activity.
American heart journal  •  1975  |  View Paper