supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Amiloride
supplement:
Citric Acid
Research Papers that Mention the Interaction
“ Amiloride significantly, albeit weakly, reduced the irritation elicited by citric acid while it weakly but significantly enhanced capsaicin-evoked irritation.”
Sensory properties of citric acid: psychophysical evidence for sensitization, self-desensitization, cross-desensitization and cross-stimulus-induced recovery following capsaicin.“The responses to citric acid were inhibited significantly more than the responses to all other stimuli with the exception of NaCl mixed with amiloride.”
Pontine gustatory activity is altered by electrical stimulation in the central nucleus of the amygdala.“In neurons classified as NaCl-best, amiloride reversibly blocked responses to NaCl, HCl, and citric acid.”
“ Amiloride (30-300 microM), which when presented alone was neither preferred nor avoided, significantly reduced the aversiveness of citric acid at pH 2.4, similar to its effect on NaCl aversiveness.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback