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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Amiloride
supplement:
Cardiac Glycosides
Research Papers that Mention the Interaction
“ Amiloride has been reported to reduce the positive inotropic and toxic actions of cardiac glycosides in patients as well as in experimental animals.”
Effects of amiloride and ouabain on contractile state, Ca and Na fluxes, and Na content in cultured chick heart cells.“The antagonism of cardiac glycoside actions was best observed during the decline in developed tension elicited by amiloride subsequent to its initial positive inotropic effect.”
“These results indicate that amiloride antagonizes the positive inotropic and toxic effects of cardiac glycosides.”
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