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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Amikacin
supplement:
Zinc Chloride
Research Papers that Mention the Interaction
“ABSTRACT In vitro activity of the aminoglycoside … [AAC(6′)-Ib] was inhibited by ZnCl2 with a 50% inhibitory concentration (IC50) of 15 μM. Growth of … harboring aac(6′)-Ib in cultures containing 8 μg/ml amikacin was significantly inhibited by the addition of … complex with the ionophore pyrithione (ZnPT).”
Inhibition of Aminoglycoside 6′-N-Acetyltransferase Type Ib by Zinc: Reversal of Amikacin Resistance in Acinetobacter baumannii and Escherichia coli by a Zinc Ionophore
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