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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Amikacin
supplement:
Antioxidants
Research Papers that Mention the Interaction
“Modulation of melanogenesis and the antioxidant status of melanocytes resulting from the use of amikacin in vitro may explain a potential role of melanin and melanocytes in the mechanisms of aminoglycosides ototoxic effects in vivo.”
Modulation of melanogenesis and antioxidant defense system in melanocytes by amikacin.“Our findings showed that the activities of the antioxidant enzymes such as superoxide dismutase (p<0.001, 62.2%), catalase (p<0.05, 47.5%) were significantly lowered along with increase in the MDA levels (66.0%) after the single treatment of amikacin as compared to control group.”
Fixed dose combination of cefepime plus amikacin prevent oxidative stress in liver of Mus musculus mice.“All antioxidant enzymes had significantly lower activity in the amikacin group (p < or = 0.05) than in the control group.”
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