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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Amifostine
supplement:
Selenium
Research Papers that Mention the Interaction
“In an animal model, the … tested was that pentoxifylline, selenium , or misoprostol, used … combination with amifostine , would significantly reduce longitudinal growth loss during one radiation dose exposure to a greater extent than the … provided by only amifostine without increased morbidity or mortality or adverse effects on bone mineral density.”
“The tibial length discrepancy in the selenium and amifostine group was 12.1 ± 0.8%, less than the 15.5 ± 2.6% tibial length discrepancy in the animals treated with amifostine alone, and less than the mean 18.8% tibial length discrepancy in the radiated limbs without radioprotection.”
Combinations of Radioprotectants Spare Radiation-Induced Damage to the Physis“Some data imply that pretreatment with selenium (Se) and the radio- and chemoprotector, amifostine (WR-2721), may confer a protective effect.”
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