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Last Updated: 3 years ago

Possible Interaction: Amifostine and Selenium

supplement:

Selenium

Research Papers that Mention the Interaction

In an animal model, the … tested was that pentoxifylline, selenium , or misoprostol, used … combination with amifostine , would significantly reduce longitudinal growth loss during one radiation dose exposure to a greater extent than the … provided by only amifostine without increased morbidity or mortality or adverse effects on bone mineral density.
The tibial length discrepancy in the selenium and amifostine group was 12.1 ± 0.8%, less than the 15.5 ± 2.6% tibial length discrepancy in the animals treated with amifostine alone, and less than the mean 18.8% tibial length discrepancy in the radiated limbs without radioprotection.
Clinical orthopaedics and related research  •  2004  |  View Paper
Some data imply that pretreatment with selenium (Se) and the radio- and chemoprotector, amifostine (WR-2721), may confer a protective effect.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer  •  1998  |  View Paper