“Thus, on cultured hippocampal neurons, amantadine preferentially inhibits nicotinic currents.”
“Thus, the noncompetitive effects of amantadine on the type … alpha 7 nAChR. The slowly desensitizing, alpha-bungarotoxin-insensitive nicotinic currents of type II, which is inhibited by dihydro-beta-erythroidine and is mediated by … is mediated by alpha 3 beta 4 nAChRs, were also sensitive to inhibition by amantadine.”