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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Amantadine
supplement:
Cocaine
Research Papers that Mention the Interaction
“The behavioral effects of amantadine in normal and reserpinized rats were potentiated by l-DOPA, nialamide, desipramine and, in particular, by cocaine.”
The effect of amantadine on motor activity and catalepsy in rats“In contrast, in both the saline control and daily injection subjects amantadine treatment during withdrawal resulted in a slight, but statistically significant, reduction in the behavioral effects of cocaine.”
Continuous or intermittent cocaine administration: Effects of amantadine treatment during withdrawal“Moreover, cocaine (5 x 10'6 g/ml) inhibited the positive inotropic effect of Ada and Ada (10'5 g/ml) poten tiated the response of atria to noradrenaline.”
“ Cocaine withdrawal symptom severity may predict response to medications that relieve cocaine withdrawal symptoms, such as amantadine.”
Amantadine treatment for cocaine-dependent patients with severe withdrawal symptoms
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