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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Amantadine and Cocaine



Research Papers that Mention the Interaction

The behavioral effects of amantadine in normal and reserpinized rats were potentiated by l-DOPA, nialamide, desipramine and, in particular, by cocaine.
Psychopharmacologia  •  2004  |  View Paper
In contrast, in both the saline control and daily injection subjects amantadine treatment during withdrawal resulted in a slight, but statistically significant, reduction in the behavioral effects of cocaine.
Pharmacology Biochemistry and Behavior  •  1994  |  View Paper
Moreover, cocaine (5 x 10'6 g/ml) inhibited the positive inotropic effect of Ada and Ada (10'5 g/ml) poten tiated the response of atria to noradrenaline.
Japanese journal of pharmacology  •  1967  |  View Paper
Cocaine withdrawal symptom severity may predict response to medications that relieve cocaine withdrawal symptoms, such as amantadine.
Expert review of neurotherapeutics  •  2002  |  View Paper