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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Aluminum Hydroxide
supplement:
Saponin
Research Papers that Mention the Interaction
“A significant increase in the risk of T. foetus clearance was found with the combination of saponin plus aluminum hydroxide based vaccine (hazard ratio, 5.12; 95% confidence interval, 2.04-12.83).”
“The median time for clearance of infection was 69days in non-immunized animals, 55days in animals treated with aluminum hydroxide, 41days with oil-in-water or saponin based vaccines or with a commercial vaccine and 27days in animals treated with saponin plus aluminum hydroxide.”
Clearance of Tritrichomonas foetus in experimentally infected heifers protected with vaccines based on killed-T. foetus with different adjuvants.“The addition of aluminium hydroxide or incomplete Freund’s adjuvant significantly enhanced neutralizing antibody titres whereas the addition of saponin dramatically depressed the titres.”
“The toxicity of saponin was decreased in the presence of aluminium hydroxide gels.”
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