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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Aluminum Hydroxide and Saponin

Research Papers that Mention the Interaction

A significant increase in the risk of T. foetus clearance was found with the combination of saponin plus aluminum hydroxide based vaccine (hazard ratio, 5.12; 95% confidence interval, 2.04-12.83).
The median time for clearance of infection was 69days in non-immunized animals, 55days in animals treated with aluminum hydroxide, 41days with oil-in-water or saponin based vaccines or with a commercial vaccine and 27days in animals treated with saponin plus aluminum hydroxide.
Vaccine  •  2017  |  View Paper
The addition of aluminium hydroxide or incomplete Freund’s adjuvant significantly enhanced neutralizing antibody titres whereas the addition of saponin dramatically depressed the titres.
Research in veterinary science  •  1974  |  View Paper
The toxicity of saponin was decreased in the presence of aluminium hydroxide gels.
Research in veterinary science  •  1969  |  View Paper